CAMBRIDGE / LONDON (IT BOLTWISE) – A new startup has developed a breakthrough technology that could revolutionize the delivery of cancer drugs via oral tablets. The use of 3D printed fibers, which turn into a gel in the stomach, enables the active ingredients to be released evenly. This innovation could increase the effectiveness of cancer treatments and reduce side effects.
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Treating cancer with oral medications is widely used due to their convenience. But the rapid dissolution of these medications in the stomach often leads to a sudden increase in drug levels in the blood, which can cause side effects. In addition, the concentration drops quickly after this initial increase, which can reduce the effectiveness of the treatment.
The startup Enzian Pharmaceutics, founded by Aron Blaesi and Nannaji Saka, has developed an innovative solution: an oral tablet that releases medication evenly over a longer period of time. These tablets are made of tiny, 3D printed fibers that turn into a gel-like substance in the stomach and release the active ingredient in a controlled manner.
The company is currently testing the ability of its tablets to remain in the stomachs of healthy volunteers. In about a year, Enzian plans to test the technology on cancer patients to improve its effectiveness and safety. Blaesi believes that many oral cancer drugs could benefit from this technology.
The development of these tablets began with the realization that the microstructure of tablets influences the release rate of drugs. Blaesi and Saka used 3D printing techniques to create precise microstructures that enable controlled release. This technology could revolutionize cancer treatment by increasing effectiveness and reducing side effects.
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