HOUSTON / LONDON (IT BOLTWISE) – A new study from the MD Anderson Cancer Center has produced surprising results on the effects of mRNA vaccines in cancer patients. The study shows that patients with skin or lung cancer who receive an mRNA vaccination against Covid-19 survive significantly longer. The effect is particularly notable in patients whose tumors are considered to be immunologically cold, as the vaccination activates the immune system and improves the effectiveness of immunotherapy.
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Recent research from MD Anderson Cancer Center has revealed an unexpected link between mRNA vaccines and cancer patient survival rates. Originally developed to protect against the Covid-19 virus, these vaccines also appear to boost the immune systems of cancer patients and increase their chances of survival. A significant increase in survival time was observed, particularly in patients with skin or lung cancer who received immunotherapy.
The study shows that vaccinated patients with non-small cell lung cancer survived an average of almost 37 months, while unvaccinated patients only survived about 21 months. For metastatic melanoma, the survival rate after three years was 67 percent compared to 44 percent for unvaccinated patients. These effects only occurred with mRNA vaccines such as those from Biontech/Pfizer and Moderna, while classic vaccines had no influence on the course of the disease.
The mechanism behind this phenomenon appears to lie in the strong activation of the immune system by the mRNA vaccination. Within 24 hours of vaccination, the body produces large amounts of type I interferon, a signaling substance normally released during viral infections. This signal acts like a wake-up call for the immune cells, which can then attack tumor cells. Particularly in tumors that are considered immunologically cold, vaccination can change the environment and make immunotherapy more effective.
The timing of vaccination plays a crucial role. The best results were achieved when vaccination occurred within 100 days before or after starting immunotherapy. This timing appears to enhance the effect of immunotherapy, resulting in a significant increase in survival time. The researchers emphasize that although these findings are promising, further studies are needed to understand the precise mechanisms and the full potential of mRNA vaccines in cancer therapy.
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